Impaired Hearing in Mitochondrial Disorders
نویسندگان
چکیده
منابع مشابه
Impaired Hearing in Mitochondrial Disorders
about the frequency of central and peripheral auditory system affection in 73 patients with a mitochondrial disorder (MID) due to mitochondrial DNA (mtDNA) point mutations or a single mtDNA deletion. We had the following comments and concerns. How can the authors be sure that impaired hearing (IH) was due to mtDNA‑mutations and not due to one of the frequent other genetic defects associated wit...
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The frequency of three mitochondrial point mutations, 1555A-->G, 3243A-->G, and 7445A-->G, known to be associated with hearing impairment, was examined using restriction fragment length polymorphism (RFLP) analysis in two Japanese groups: (1) 319 unrelated SNHL outpatients (including 21 with aminoglycoside antibiotic injection history), and (2) 140 cochlear implantation patients (including 22 w...
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Objectives: The aim of the present study was to investigate satisfaction levels with hearing aids in daily life of older adult users, in addition to associated factors. Methods & Materials: In this cross sectional study, 32 subjects with moderate to severe sensory neural hearing loss (mean age; 63.5±9.8 Yrs) and different socio-economic status, referred to private practice audiology clinic (...
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Mutations in mitochondrial DNA (mtDNA) have been shown to be an important cause of sensorineural hearing loss (SNHL). In this study, we performed a clinical and genetic analysis of 169 hearing-impaired patients and some of their relatives suffering from idiopathic SNHL, both familial and sporadic. The analysis of four fragments of their mtDNA identified several polymorphisms, the well known pat...
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Introduction: Hearing loss is the most frequent sensory disorder occurs in 1/1000 newborns. About 50% of hearing loss cases are due to genetic causes. Mutation in MTRNR1(A1555G), MTTL1(A3243G) and MTTS1(A7445G) are known to be one of the important cause of nonsyndromic Sensorineural hearing loos in some populations. This study aims to demonstrate the frequency of three mitochondrial mutatio...
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ژورنال
عنوان ژورنال: Chinese Medical Journal
سال: 2015
ISSN: 0366-6999
DOI: 10.4103/0366-6999.159367